Michael Morale

Teri – I’ve never really heard of children suffering from seizures with regards to their Spinraza injections, but if your son didn’t have seizures before starting Spinraza, there may be a correlation.

I agree with Alyssa when she said that risdiplam will be going to a different part of the body. Since risdiplam is going to be an oral treatment,…[Read more]

Lupa,

I’m glad that your procedure went well. It can be somewhat unnerving to be too close to people that have tested positive. When my caregiver dropped me off at the hospital, I had to have my mask on, and I had to go through 2 different checkpoints before I was admitted into the hospital itself.

When I got to the registration desk, they a…[Read more]

Hey Alyssa,

Everything went well. I went into the hospital about 10:45 AM, and after the procedure was completed and I had one hour to lay on my back, I was released from the hospital around 3:30 PM CST.

Hope you’re doing well, and have a blessed day.

I personally don’t think that this would be considered as receiving a combination therapy. You are correct when you say that this was one of the prerequisites, and the example that I gave you regarding the gentleman that I know that had been on Spinraza and then moved to risdiplam in January 2019 is an example of this.

I don’t believe that any of…[Read more]

Mike – I’ve never heard anything regarding a combination trial, and I personally don’t think that this would be an option during any clinical trial setting. I say this because during all clinical trials, the pharmaceutical companies are testing the efficacy and safety of a certain treatment that is trying to get approval from the FDA. I don…[Read more]

Crystal –

My name is Michael Morale, and I’m the Senior Director of Multi-Channel Content for SMA News Today, along with their parent company, BioNews Services.

I read your comments about the pain that you’re going through with regards to your buttocks and your tailbone. I wanted let you know that there are so many of us that are going through…[Read more]

Hi Mike – The NCT number that you gave, (NCT03032172), An Open-Label Study to Investigate the Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of RO7034067 in Adult and Pediatric Patients With Spinal Muscular Atrophy, is the Jewelfish trial that started back in January 2017.

If you go to http://www.clinicaltrials.gov and enter the NCT number…[Read more]

Lupa –

It’s probably been within the last 6 to 8 months that I started noticing some strength differences in my hands, and while I do believe that Spinraza has slowed the progression of my disease, it hasn’t stopped the progression totally. I’ve talked to other people who have said the same thing regarding their condition, and given that this…[Read more]

Derek –

I greatly appreciate you commenting on my video. My name is Michael Morale, and I’m the Senior Director of Multi Channel Content for SMA News Today, along with their parent company, BioNews Services

We just recorded a podcast where we did a roundtable discussion, and the subject of a combination therapy was brought up during this…[Read more]

Risdiplam, in my opinion, is going to be a major player within the SMA community. Even though it will work on the SMN2 gene, similar to Spinraza, the opportunity that it provides those who are unable to take Spinraza due to medical conditions, could give these individuals the ability to start on a viable treatments for SMA.

Some of the advantages…[Read more]