A plant used in traditional Chinese medicine boosts the production of functional survival motor neuron (SMN) protein — whose lack underlies…
Articles by Joana Carvalho, PhD
Electrotherapy combined with physical exercise may be used to improve motor function in people with spinal muscular atrophy (SMA)…
Although damage to motor neurons characterizes spinal muscular atrophy, problems with lipid (fat) metabolism are an important feature of SMA that…
Severe brain abnormalities are evident in children born spinal muscular atrophy type 0, also known as prenatal onset SMA, who…
Clinicians have described the case of an Iranian teenager with a rare type of spinal muscular atrophy (SMA) associated…
A small RNA molecule called miR-23a can prevent neuron degeneration and muscle wasting by acting as a protective modifier in…
Long-term treatment with Biogen‘s Spinraza (nusinersen) showed clinically meaningful improvement in the motor function of children ages…
A global dysregulation affecting multiple signaling cascades operating inside motor neurons may be the underlying cause of spinal and bulbar…
Zolgensma (AVXS-101), an investigational gene therapy for patients with spinal muscular atrophy (SMA), improves motor function and prolongs…
Valproic acid, or valproate, is a relatively safe drug that improves gross motor function in patients with spinal…