Patient-derived Cell Models Created for SMA-LED Research
Researchers have developed and validated four new cell lines derived from four patients with spinal muscular atrophy (SMA) with…
Articles by Lindsey Shapiro, PhD
Greater SMA Severity Seen in Men Than Women: Natural History Study
Among adults with spinal muscular atrophy (SMA), men show signs of greater disease severity than women, particularly as young…
Higher SMA Rate in Japan Linked to Awareness of New Therapies: Study
The incidence of infantile spinal muscular atrophy (SMA) has increased in Japan since 2016 and this could be related…
Boy With SMA Type 2 Able to Walk, Play Wearing Exoskeleton at Home
For a boy with spinal muscular atrophy (SMA) type 2, wearing a robotic gait-training device at home led to…
Leptin Levels Linked to BMI, Not Motor Function in SMA 2 and 3
Levels of the hunger hormone leptin are not associated with motor function in children and adolescents with spinal muscular…
Moderate Strength Training Benefits Man With SBMA
Moderate-intensity resistance training led to gains in muscle strength, balance and functional improvements in a man with mild impairments due…
New Gene Therapy Shows Potential for Safety, Efficacy in Mouse Model
A second-generation investigational gene therapy for spinal muscular atrophy (SMA) showed greater safety and efficacy than an earlier version,…
2 UK Nonprofits Fund PhD Student to Study SMA Mechanisms, Treatments
A couple of nonprofits in the U.K. will jointly sponsor a PhD student’s research into the mechanisms underlying nerve degeneration…