Author Archives: Kara Elam

Impaired Mitochondrial Dynamics Play Role in SMA Pathology

The degeneration of spinal motor neurons in spinal muscular atrophy (SMA) may be the direct result of abnormal mitochondrial (energy source of cells) transport and morphology and subsequent reduced mitochondrial health. These are the conclusions of a study preformed by an international team of collaborative researchers led by scientists from the…

Spinal Muscular Atrophy Study Points to Blood Vessel Defects

U.K. researchers funded by the SMA Trust have found that insufficient blood supply may well contribute to motor neuron loss in spinal muscular atrophy (SMA). The study entitled, “Vascular defects and spinal cord hypoxia in spinal muscular atrophy,” was published in the latest edition of the Annals of…

SMA Drug Developer AveXis Forms AveXis EU as European Subsidiary

Dallas, Texas-based AveXis, Inc., a biotechnology company currently developing an experimental therapy for Spinal Muscular Atrophy (SMA) through the use of innovative gene therapy, recently announced that they have established a European Union (EU) based wholly-owned subsidiary called AveXis EU, Ltd.  This subsidiary will be used by AveXis to…