Certain motor neurons resistant to degeneration in SMA: Study
While certain populations of motor nerve cells — and the muscles they connect to…
Articles by Lindsey Shapiro, PhD
Top 10 SMA stories of 2023
Throughout 2023, SMA News Today brought you the most up-to-date news on scientific breakthroughs and treatment advances related to…
New ASAH1 mutation identified in fetus with severe complications
A novel mutation in the ASAH1 gene was identified as the cause of severe fluid buildup with swelling (hydrops fetalis) and…
3 SMA type 1 patients show better finger, facial control with Spinraza
Three young people with severe spinal muscular atrophy (SMA) type 1 and treated with Spinraza (nusinersen) after their…
Growth-friendly scoliosis surgery found safe, effective in SMA type 1
A type of surgery to correct scoliosis, a spine deformity, was found to be generally safe and effective in…
Pediatric dosing of acetaminophen advised for SMA adults, children
People with spinal muscular atrophy (SMA) cleared acetaminophen, a common ingredient in pain medications, slower than healthy people, but…
SMN loss seen to affect key brain signaling molecule, norepinephrine
Disruptions to norepinephrine (NE), a brain signaling molecule, appear to be due to SMN protein loss and could contribute to…
SMA-specific tests needed to better measure fatigue in adults: Survey
Existing tools for assessing fatigue may not be enough to capture differences in fatigue severity between adults with different types…
One-third of adults with SMA show signs of poor lung function
About a third of adults with spinal muscular atrophy (SMA) show signs of poor, and abnormal, lung function, according…
PRMT inhibitor alone or as Spinraza add-on shows promise
Adding a small molecule to a low dose of Spinraza (nusinersen) led to enhanced therapeutic benefits in a mouse…