The 4 Types of Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a debilitating, severe disease that affects mainly children, shutting down their body, their muscles and organs but in varying ways according to type. There are four SMA types: type 1, 2, 3, and 4.

To help you understand a little more about the different types of SMA, here’s a list:

SMA TYPE 1

Also known as Werdnig-Hoffmann disease, type 1 is the most severe and common type of SMA. It is commonly diagnosed in a child’s first six months of life. More than 60% of spinal muscular atrophy cases are the often fatal type 1.

Read our article “Promising Results of SMA Therapy in Mice Targets ‘Backup Gene’ SMN2.”

SMA TYPE 2

Is usually diagnosed in a child between six months and two years old. Those who live with this type of SMA can typically sit by themselves but they are unable to walk and will require a wheelchair.

Find out how researchers have developed new mice models for SMA types 2 and 3.

SMA TYPE 3

Also known as Kugelberg-Welander disease, type 3 is normally diagnosed between 18 months and three years old. Patients with this type can initially walk, but their mobility become limited with growth.

Find out how researchers have developed new mice models for SMA types 2 and 3.

SMA TYPE 4

Type 4 is very rare. It usually appears during adulthood and leads to mild motor impairment. While symptoms can begin as early as age 18, they usually begin after age 35.

Read more on how a PCR mode can help determine SMA type.

SMA News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.