In SBMA, Cold Temperatures Slow Nerve Impulses to Arm Muscles
Men with spinal and bulbar muscular atrophy (SBMA) had slower nerve impulses leading to their forearm muscles when their…
Articles by Steve Bryson, PhD
SMA Research Boosted by 2 MDA Grants Totaling $510K
The Muscular Dystrophy Association (MDA) has awarded $17 million among 70 new grants toward neuromuscular disease research, including $510,000…
Study May Reveal New Biomarkers Specific to SMA Types
New protein biomarkers that can distinguish between the different types of spinal muscular atrophy (SMA) were identified in a…
Respiratory Muscle Training May Help Breathing Function in SMA
Respiratory muscle training in spinal muscular atrophy (SMA) has the potential to stabilize or improve breathing function, a study…
Muscle Twitches Detected by Ultrasound May Aid Late Diagnosis
Muscle fasciculations, or twitches, in adolescents and adults with later onset forms of spinal muscle atrophy (SMA) were detected…
‘Groundbreaking’ Cybernetic Therapy Improves Walking in SBMA
Two years of training with a wearable cyborg hybrid assistive limb (HAL), combined with leuprorelin therapy, markedly improved the walking…
Mouse Models Show Neuromuscular Junction Alterations in SBMA
Scientists have revealed specific alterations to the neuromuscular junction (NMJ) — the place where nerves connect to the muscle they…
Nonambulatory SMA Patients Show Gains With 2 Years of Apitegromab
Two years of treatment with the investigational therapy apitegromab continued to improve motor function in Spinraza-treated children and young…
MicroRNAs in Blood May Predict Spinzara Response in Type 1 Patients
MicroRNAs isolated from the bloodstream of patients with infant-onset spinal muscular atrophy (SMA) type 1 before treatment were related…
Higher Spinraza Dose May Be More Effective, Modeling Study Predicts
A new modeling study predicts that higher doses of Spinraza (nusinersen) may improve its effectiveness compared with the approved…