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This topic has 6 replies, 4 voices, and was last updated 2 years, 7 months ago by DeAnn R.

  • Author
    • #12445
      Michael Morale

      In the first episode of my new video series “The Morale Monologue”, I discuss Cytokinetic Pharmaceutical’s upcoming announcement of their Phase 2 clinical trial using their drug Reldesemtiv. (Previously known as CK-2127107) Cytokinetics is planning on making this announcement during the 2018 Cure SMA Annual Conference, scheduled to be held at the Hilton Anatole Hotel in Dallas Texas from June 14 – June 17.

      During Cytokinetic’s Phase 2 clinical trial, their primary objective was to see if treatment could improve patients’ muscular function and respiratory capacity, and ease fatigue. Secondary goals included measures of the treatment’s safety, tolerability, and pharmacodynamics, or how the therapy was absorbed, distributed and metabolized, and then expelled.

      I not only review the article, I also provide my perspective and opinions regarding what I believe to be Cytokinetic’s next move regarding the future of this drug, and how this future decision will impact those of us with SMA.

      Be sure to subscribe to the SMA News Today YouTube channel so that you don’t miss an episode of this vlog, and you can also connect with me right here on the forums page.

    • #12451
      Kevin Schaefer

      I’m excited to hear the specific announcement at the conference this year. Spinraza has yielded some great results, but it’s exciting to see other drugs in the pipeline as well. AveXis is really making advancements as well.

      Looking forward to the conference!

    • #12453
      Michael Morale

      I hope everyone likes my first video.  Thanks to Marta and Kevin Schaefer for their input and assistance.

    • #12454
      DeAnn R

      That’s great Michael! It sure will be interesting to follow. Thanks for keeping us up to date and giving us your point of view.

    • #12455
      Michael Morale

      Thanks DeAnn.

    • #12497
      Adnan Hafizovic

      Good video Michael,I feel Cytokinetic will be more effective then Spinraza and less cheaper.

      • #12591
        DeAnn R

        Fingers crossed!

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