I recall some of what you are experiencing when I started Evrysdi. I no longer have those feelings. I believe each person’s body learns to accept Evrysdi. For me, it was mainly my bowels. Now (8 months later) my body has adjusted nicely and I rarely have problems. I’m one who doesn’t like taking any forms of medication, so I sometime take a small amount of wine or other alcohol drink before bedtime, which helps me fall asleep easier. Good luck and I hope it gets better for you!